orphan disease
n.— «The WHO has termed genetic and orphan diseases (an orphan disease is defined as a condition that affects less than 200,000 people nation-wide) as a major future health challenge.» —“Stress on diagnostic shift” Gulf Times (Doha, Qatar) Apr. 9, 2005. (source: Double-Tongued Dictionary)
Further reading
Steven from San Antonio, Texas, seeks a word that means “the opposite of trauma.” Perhaps eustress, literally “good stress”? Or harmonization? Placid? Is there a better term for this? This is part of a complete episode...
Understanding the varieties of conversational styles can mean the difference between feeling you’re understood and being insulted. “High-involvement” speakers interrupt or talk along with someone else to signal their enthusiasm...