shack-wacky
adj.— «“Poison Pinky,” it was agreed, had gone “shack-wacky.”» —by Edith Kneipple Roberts Tamarack , 1940. (source: Double-Tongued Dictionary)
Further reading
Pizey is an old dialectal term from the United Kingdom that means “peevish” or “irritable.” Pizey and pize, as in A pize upon you! may be related to the word poison. This is part of a complete episode. Transcript of...
The plant jimson weed has dangerous hallucinogenic effects. The weed takes its name from Jamestown, Virginia. In 1676, settlers there ingested the weed, and its poisonous effects were vividly described a few years later in a volume called The...